«L'emploi des moyennes en physiologie et en médecine ne donne le plus souvent qu'une fausse précision aux résultats en détruisant le caractère biologique des phénomènes. » . Claude Bernard
This quote from the father of modern physiology and medicine highlights the need for measuring biological phenomena at their relevant scale. The recent explosion in techniques allowing to interrogate the molecular content at the single cell level now allows to unleash the full power of the cell theory formulated in 1839.
We are currently witnessing an explosion in the wealth of data produced at the single cell level, but the theoretical framework in which those data can be analyzed needs to be updated. Although it is still too early to provide definivite standard approaches, this BioSyL workshop aims at providing both biologists and bioinformaticians with a crash course in the relevant analysis techniques.
Where: Salle des thèses Chantal Rabourdin-Combe, ENS de Lyon, site Monod, 46 Allée d'Italie, 69007 Lyon
When: March 16, 2018
14h00 – 14h30: Olivier Gandrillon (LBMC): Why are single cell data so special? The bursty nature of gene expression when seen at the single cell level (presentation Olivier Gandrillon)
14h30 – 15h00: Arnaud Bonnaffoux (LBMC): A pipe-line for scRTqPCR analysis (presentation Arnaud Bonnaffoux)
15h00 – 15h30: Coffee break
15h30 – 16h00: Laurent Modolo (LBMC): Analysing single cell RNAseq (presentation Laurent Modolo)
16h00 - 16h30: Helena Todorov (CIRI; DAMBI): Trajectory inference from single cell data (presentation Helena Todorov)
16h30 - 17h00: Questions
Contact : Olivier Gandrillon 04 72 72 85 95 Olivier.Gandrillon@ens-lyon.fr
