| Disciplines | Biology, Physics |
|---|---|
| Research fields | Biophysics, Statistical physics, Bioinformatics, Multi-scale models, Molecular Biology, Structure biology, Omics, Genome, Dynamic systems, Network modelling |
| Supporting organisms | CNRS, ENS de Lyon, UCBL |
| Geographical location | ENS de Lyon (Campus Charles Mérieux) |
| Lab |
Laboratory of biology and modelling of the cell (LBMC)
|
| Team leader | Daniel Jost |
| Webpage | http://www.ens-lyon.fr/LBMC/equipes/biologie-physique-de-la-chromatine |
In close connection with experimental biology, our research addresses generic or specific biological questions on chromatin and gene regulation by developing physical and computational models. Particularly, we focus on the spatio-temporal dynamics of eukaryotic chromosomes. Our research tackles important questions regarding the coupling between 3D structure and functions of chromatin. Our objective is to provide some universal principles driving chromatin folding and regulation, while contextualizing our approaches to fundamental, specific problems of 3D genomics.
