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SeMoVi - September 19th, 2007

SeMoVi
14h00 - 15h00

Bas Kooijman, Vrije Universiteit, Amsterdam
Dynamic Energy Budget theory for metabolic organisation and its applications

15h00 - 15h30 Pause café
15h30 - 16h30

James Devillers, CTIS
QSAR modeling in (eco)toxicology

Elise Billoir, LBBE
On the use of Bayesian Inference in Ecotoxicology

16h30 - 17h00 Discussion générale

 

Bas Kooijman, Vrije Universiteit, Amsterdam
Dynamic Energy Budget theory for metabolic organisation and its applications

Metabolic organization of individual organisms is basic to life. It seems to follow simple quantitative rules that can be understood from basic physical chemical principles. These rules quantify how individuals acquire and utilize energy and nutrients, while cycling through their life stages. Dynamic Energy Budget (DEB) theory identifies the most basic rules, and links them together in a consistent framework. The DEB theory applies to all species of organisms (unicellular as well as multicellular ones) and links various levels of biological organization; this multi-level approach is considered to be essential for the understanding of life processes. Many popular empirical models turn out to be special cases of the standard DEB model, or very close numerical approximations. The lecture will discuss some recent progress in

  • formalisation of the theory
  • evolutionary aspects of metabolic organisation
  • parameter estimation
  • applications in ecotoxicity and biotechnology

 

More information about research on DEB theory can be found at http://www.bio.vu.nl/thb/deb/
A general introductory paper to the DEB theory can be found athttp://www.bio.vu.nl/thb/research/bib/Kooy2001.html

 

 

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