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SEMOVI - The 4D Genome

Semovi - The 4D genome - Tuesday the 15th of October 2019 - ENS de Lyon - Amphi SVT


“People have started to realize, you can’t answer this question by just doing an imaging experiment, or just doing a Hi-C experiment, or just doing a biochemical experiment or coming up with a clever molecular or biophysical model that you simulate in the computer. We will have to work together and do all these things in some kind of a coherent manner, because it’s probably going to involve all these disciplines.”

Job Dekker, University of Massachusetts Medical School in Worcester, 9 MAY 2019 | VOL569 | NATURE 293


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9h00 – 10h00: Olga K. Dudko, University of California San Diego. 

"On the Border of Order: Chromosomal Organization in Space and Time"



10h00 – 10h30: coffee break



10h30 – 11h00: Yad Ghavi-Helm, IGFL

"Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression"



11h00 – 11h30: Alexandre Laverré, LBBE

"Using Promoter Capture Hi-C data to understand evolution of expression regulatory landscapes in vertebrates"



11h30 – 12h00: Cyril Bourgeois, LBMC

"Role of RNA helicases DDX5/17 in the connection between local 3D gene organization, alternative splicing and transcription termination"


12h00 – 14h00: Lunch



14h00 – 14h30: Sam Meyer, MAP

" Genome architecture shapes ancestral transcriptional regulation by DNA supercoiling "


14h30 – 15h00: Patrick Lomonte, INMG

" Genomes nuclear positioning to control transcriptional activity of herpes simplex virus 1. The role of promyelocytic leukemia nuclear bodies "


15h00 – 15h30: Jean-Michel Arbona, LBMC

"Modeling of spatio-temporal replication program"


15h30 – 16h00: coffee break



16h00 – 17h00: Lothar Schermelleh, University of Oxford 

" Functional chromatin organisation in mammalian cells - lessons from 3D super-resolution imaging "






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