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PhD opportunity: COSMIC, COmbatting disorders of adaptive immunity with Systems MedICine

 

A PhD research position is available at IBM – Zurich Research Laboratory, as a part of the H2020 COSMIC consortium, focused on understanding disorders of the adaptive immune system.

Background: EU countries face large health challenges to combat chronic diseases. Recently, systems medicine has emerged as a promising discipline to accelerate the translation of basic research into applications for improved diagnostics and personalized treatment. Its power arises from the integration of laboratory and computational approaches crossing research disciplines and sectors to solve clinical questions.

Approach: COSMIC will focus on B-cell neoplasia and rheumatoid arthritis, prototypical diseases originating from abnormal functioning of immune cells, often resulting in similar antigen specificities. The successful candidate will develop mechanistic models to help unravel disease mechanisms, and to identify strategies for optimal personalized patient treatment.

Starting date: 01/06/18.

Requirements:

- Strong background in physics, mathematics, computer science or similar. - Working knowledge of statistics and mathematical modeling.
- Working knowledge of Matlab, R or equivalent.
- Comfortable knowledge of C or C++.

In addition, experience in systems biology or systems medicine, as well as machine learning would be helpful, but not essential.

Interested candidates, please send an application including CV and reference letters to: Dr. Maria Rodriguez Martinez <mrm@zurich.ibm.com>.

Diversity: IBM is committed to diversity at the workplace. With us you will find an open, multicultural environment. Excellent flexible working arrangements enable both women and men to strike the desired balance between their professional development and their personal lives.

Keywords: Mechanistic models of cancer, systems modelling, statistical inference.