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Genomic Scientist Position at SANOFI

Genomic Scientist Position

Position duration: 18 months (CDD)
City: Vitry sur Seine, France
Starting date: 01/10/2017
Company: Sanofi Chimie – Industrial Affairs, Vitry sur Seine

Contact: Anne-Sophie COQUEL (Head of Genomics) Email: anne-sophie.coquel@sanofi.com

Valid until 15/09/2017

Description of the position:
Sanofi is producing biomolecules by fermentation using micro-organisms. The use of strain engineering is necessary to improve the production of biomolecule of interest. The analysis of OMICS data is a valued knowledge to understand which genes-proteins are involved directly or indirectly in the production. Comparing the genomes allows highlighting genes and mutations of interest. The latter are key clues for the strain engineering.

Missions:

Genome comparisons
OMICS data (genomic, transcriptomic and proteomic) analysis and correlation between all OMICS data and data such as fermentation or metabolomic data
Scientific and technologic watch
Inter-disciplinary interactions with fermentation and analytics teams
Management of different projects
Production of results from the raw/assembled data
Writing reports, procedures, documentation
Understanding of the tools developed in the department
Modification and improvement of the bioinformatics pipelines if necessary

Education:

Genomic and bioinformatic backgrounds are mandatory
Required Master 2/ Engineer in genomics-bioinformatics (bac +5) with experience Postdoc in genomics-bioinformatics appreciated

Know-how – Expertise:

Knowledge in NGS analysis tools
Genome comparison (alignments, rearrangements, analysis of mutations) Experience with coding and programming languages (Python, Perl, etc.)

Valued knowledge:

Insights regarding the filamentous bacteria and/or actinomycetes and the production of antibiotics: synthetic biology, genomics and metabolic pathways
Lab experience on actinomycetes

Languages:

High level of written and spoken English (oral and written communication) French is an asset

Soft skills:

Abilities to work as a multi-cultural team

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